Fructosamine
NBT | Nitroblue tetrazolium chloride reduction method
| REF | Volume |
|---|---|
| N/A | N/A |
Product description:
Fructosamine is the general name for glycated proteins which become stable ketoamine, and is
measured by the reduction chromogenic reaction with nitroblue tetrazolium as the substrate, by
utilizing the strong reducing power of fructosamine in alkaline solution. Fructosamine is not
affected by anemia or variant hemoglobin. Since the metabolic turnover of albumin (2-3 weeks)
which occupies most of serum protein is faster than that of hemoglobin, measurement of
fructosamine can be used to judge intermediate-term glycemic control.
Serum fructosamine concentration measured by the reduction of nitro-blue tetrazolium in alkaline
solution, has been shown to be simple, inexpensive and useful in the assessment of glucose
homeostasis both in type I and type II diabetes mellitus. Though, fructosamine is not used for
diagnosis of diabetes; however, its usefulness in patients having anemia or variant haemoglobins
has been highly recognized. In addition, fructosamine may be helpful in patients undergoing
multiple changes in treatment or in pregnant women.
